Insulin lispro protamine is used to reduce high blood sugar levels in patients Insulin lispro protamine is injected under the skin. Humalog Mix KwikPen. HUMALOG é indicado no tratamento de pacientes com diabetes mellitus que necessitam .. médico e leve a embalagem ou bula do medicamento, se possível. 18 abr. B. Humalog Mix 50 Lilly (50% lispro/protamina e 50% lispro). 2,0. .. dicado em bula, o uso combinado de exanatide com.

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In some instances, this condition may be related to factors other than insulin, such as irritants in the skin hukalog agent or poor injection technique.

Reporting suspected adverse reactions after authorisation of the medicinal product is important. Insulin lispro did not induce fertility impairment, embryotoxicity or teratogenicity in animal studies.

The patient’s ability to concentrate and react may be impaired as a result of hypoglycaemia. Instructions for use and handling To prevent the possible transmission of disease, each pen must be used by one patient only, even if the needle is changed. Insulin lispro, sold under the brand name Humalog among others, is a fast acting insulin analog.

Humalog can be used in conjunction with a longer-acting insulin or oral sulphonylurea medicinal products, on the advice of a physician. The markings on the insulin syringe will not measure the dose correctly. Learn about Humalog Insulin Lispro Human Analog may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related This rapid onset of activity allows a Humalog injection to be given very close to mealtime. Send coupon directly to your phone. Cases of oedema have been reported with insulin therapy, particularly if previous poor metabolic control is improved by intensified insulin therapy.

For the treatment of adults with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis. Humalog should not be used if it appears cloudy, thickened, or slightly coloured or if solid particles are visible. Show table of contents Hide table of contents 1.

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Strengths Available for Humalog |

Back to top Eli Lilly and Company Limited contact details. Continue typing to refine. Clinical trials in patients with type 1 and type 2 diabetes have demonstrated a reduced number of episodes of nocturnal hypoglycaemia with insulin lispro compared to soluble human insulin.

Subcutaneous administration should be in the upper arms, thighs, buttocks, or abdomen. It may cause a rash over the whole body, shortness of breath, wheezing, reduction in blood pressure, fast pulse, or sweating. Exercise taken immediately after a meal may increase the risk of hypoglycaemia.

No specific frequency for hypoglycaemia is presented, since hypoglycaemia is a result of both the insulin dose and other factors e. Handling of the pre-filled pen Before using the KwikPen the user manual included in the package leaflet must be read carefully. Cases of cardiac failure have been reported when pioglitazone was used in combination with insulin, especially in patients with risk factors for humaloy of cardiac heart failure.

To bookmark a medicine you must sign up and log in. Insulin lispro has been shown to be equipotent to human insulin on a molar basis but its effect is more rapid and of a shorter duration. Insulin lispro maintains more rapid absorption when compared to soluble human insulin in patients with renal impairment.

If the patient is comatose, glucagon should be administered intramuscularly or subcutaneously. Acute, one month and twelve month toxicology studies produced no significant toxicity humalig.

Humalog 200 Units/ml KwikPen, solution for injection in pre-filled pen

Hypersensitivity to the active substance or to any of the excipients listed in section 6. The reduction of HbA1c would also be expected with other insulin products e. Overdose hhumalog result causing severe hypoglycemia. The patient should discard humallg needle after every injection. In some studies, reduction of nocturnal hypoglycaemia was associated with increased episodes of daytime hypoglycaemia. The number of insulin units is shown in the dose window of the pen regardless of strength and no dose conversion should be done when transferring a humaog to a new strength or to a pen with a different dose step.

When administered subcutaneously care should be taken when injecting Humalog to ensure that a blood vessel has not been entered. This is particularly important in those who have reduced or absent awareness of the warning signs of hypoglycaemia or have frequent episodes of hypoglycaemia.

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Conditions bulx may make the early warning symptoms of hypoglycaemia different or less pronounced include long duration of diabetes, intensified insulin therapy, diabetic nerve disease or medicinal products such as beta-blockers. Transferring a patient to another type or brand of insulin should be done under strict medical supervision.

After first use 28 days. The faster onset of action compared to soluble human insulin is maintained regardless of injection site. Enter medicine name or company Start typing llspro retrieve search suggestions. Needles are not included. This medicinal product should not be mixed with any other insulin or any other medicinal product. Insulin requirements may be increased by medicinal products with hyperglycaemic activity, such as oral contraceptives, corticosteroids, or thyroid replacement therapy, danazol, beta 2 stimulants such as ritodrine, salbutamol, terbutaline.

It humalob first approved for use in the United States inmaking it Transferring a patient to another type or brand of insulin Transferring a patient to another type or brand of insulin should be done under strict medical supervision. Bu,a The primary activity of insulin lispro is the regulation of glucose metabolism.

Clear, colourless, lisprp solution. However, glucose solution must be given intravenously if glucagon is not available or if the patient fails to respond to glucagon.

Patients should be advised to take precautions to avoid hypoglycaemia whilst driving. Insulin lispro maintains more rapid absorption and elimination when compared to soluble human insulin in patients with hepatic impairment. Insulin lispro takes effect rapidly and has a shorter bul of activity 2 to 5 hours when compared to soluble insulin. Humalog KwikPen is available in two strengths. Mild hypoglycaemic episodes lispto respond to oral administration of glucose or other sugar or saccharated products.